臨床試験
HiSCO-14試験 試験終了
Cavitron Ultrasonic Surgical Aspirator（CUSA）とwater-jet scalpel を併用した肝実質切離「dual-wieldparenchymal transection」の安全性・有効性に関する探索試験
HiSCO-13試験 登録受付中
切除不適Intermediate Stage肝細胞癌に対するレンバチニブおよび肝動脈化学塞栓併用療法後の外科的切除の有効性・安全性に関する多施設共同非盲検探索的臨床研究
- 概要
- 進捗状況：進行中
- 申請書等はこちら
- 登録状況
- 論文掲載
- Oshita K, Kobayashi T, Namba Y, Fukuhara S, Matsubara K, Takei D, Nakano R, Okamoto W, Sakai H, Tanimine N, Nakahara T, Kuroda S, Tahara H, Ohira M, Kawaoka T, Ide K, Imamura M, Aikata H, Ohdan H Efficacy and safety of lenvatinib–transcatheter arterial chemoembolization sequential therapy followed by surgical resection for intermediate-stage hepatocellular carcinoma beyond Up-to-7criteria: a study protocol for a multicentre,single-arm,prospective study
HiSCO-12試験 登録受付中
オキサリプラチンによる末梢神経障害に対するサージカルグローブによる圧迫療法の予防効果を検証する多施設共同第II/III相ランダム化比較試験
HiSCO-11試験 試験終了
胃切除後の膵外分泌機能不全に対するリパクレオンの有効性を検討するための研究
HiSCO-10試験 試験終了
膵体尾部切除での膵実質離断におけるprecompression法の有効性に関する多施設共同単盲検無作為化並行群間比較試験
HiSCO-09試験 試験終了
左側結腸・直腸手術における近赤外線光を用いた非侵襲的腸管組織酸素飽和度測定に関する多施設共同前向き観察研究
- 概要
- 進捗状況：症例登録を終了しました
- 申請書等はこちら
- 登録状況
- 論文掲載
- Yoshinaka H, Shimomura M, Egi H, Shimizu W, Adachi T, Ikeda S, Nakahara M, Saitoh Y, Toyota K, Yoshimitsu M, Akabane S, Yano T, Hattori M, Ohdan H Non-invasive measurement of intestinal tissue oxygen saturation for evaluation of reconstructed blood flow in rectal cancer surgery: HiSCO-09 study
HiSCO-08試験 試験終了
腹腔鏡下肝切除術における開腹移行危険因子を評価する多施設共同前向き試験
HiSCO-07試験 試験終了
膵体尾部切除での膵実質切断におけるリンフォース トライステープルとトライステープルの多施設共同単盲検無作為化並行群間比較試験
HiSCO-06試験 登録受付中
胃がん肝転移症例（同時性・異時性）に対する術前化学療法後の肝切除の有効性と安全性を評価する第Ⅱ相試験
HiSCOー06A PⅡ
胃癌肝転移症例に関する観察研究
HiSCOー06B 観察研究
HiSCO-05試験 試験終了
肝切除後血液凝固異常に対するAntithrombin III製剤投与の有効性と安全性に関する研究
- 概要
- 進捗状況：試験終了しました
- 申請書等はこちら
- 登録状況
- 論文掲載
- A multicenter randomized controlled trial comparing administration of antithrombin III after liver resection (HiSCO-05 trial).
Kuroda S, Kobayashi T, Tashiro H, Onoe T, Oshita A, Abe T, Kohashi T, Oishi K, Ohmori I, Imaoka Y, Tanaka J, Ohdan H; Hiroshima Surgical Study Group of Clinical Oncology.
Surgery. 2021 Apr 26:S0039-6060(21)00318-4. doi: 10.1016/j.surg.2021.03.057. Online ahead of print.
PMID: 33926704
HiSCO-04試験 試験終了
StageⅢ高齢者（80歳以上）大腸癌症例の予後調査 観察研究
- 概要
- 進捗状況：試験登録を終了しました
- 申請書等はこちら
- 登録状況
- 論文掲載
- Mochizuki T, Shimomura S, Nakahara M, Adachi T, Ikeda S, Saito Y, Shimizu Y, Kochi M, Ishizaki Y, Yoshimitsu M, Takakura Y, Shimizu W, Sumitani D, Kodama S, Fujimori M, Oheda M, Kobayashi H, Akabane S, Yano T, Ohdan H Survival outcomes of patients with stage III colorectal cancer aged ≥ 80 years who underwent curative resection: the HiSCO‑04
- Bekki T, Shimomura M, Saito Y, Nakahara M, Adachi T, Ikeda S, Shimizu Y, Kochi M, Ishizaki Y, Yoshimitsu M, Takakura Y, Shimizu Y, Sumitani D, Kodama S, Fujimori M, Oheda M, Kobayashi H, Akabane S, Yano T, Ohdan H Association between social background and implementation of postoperative adjuvant chemotherapy for older patients undergoing curative resection of colorectal cancers, sub‑analysis of the HiSCO‑04 study
HiSCO-03試験 試験終了
StageⅢ高齢者（80歳以上）大腸癌症例に対するUFT/LV術後補助化学療法の安全性および有用性試験
- 概要
- 進捗状況：試験登録を終了しました
- 申請書等はこちら
- 登録状況
- 論文掲載
- Okuda H, Shimomura M, Ikeda S, Nakahara M, Miguchi M, Ishizaki Y, Saitoh Y, Toyota K, Sumitani D, Shimizu Y, Takakura Y, Shimizu W, Yoshimitsu M, Kodama S, Fujimori M, Oheda M, Kobayashi H, Ohdan H. A prospective feasibility study of uracil–tegafur and leucovorin as adjuvant chemotherapy for patients aged ≥ 80 years after curative resection of colorectal cancer, the HiSCO 03 study
HiSCO-02試験 試験終了
切除不能な進行・再発大腸癌に対するTS-1/oxaliplatin (SOX) + bevacizumab療法の臨床第二相試験
HiSCO-01試験 試験終了
切除可能な大腸癌肝転移に対するXELOX とベバシズマブによる術前vs.術後化学療法の有効性に関する多施設共同ランダム化第Ⅱ/Ⅲ相試験
新規登録終了のご案内
データベース統合プロジェクト
肝癌共通データベース
- 申請書等はこちら
- 論文掲載
- Ohira M, Kobayashi T, Hashimoto M, et al: Prognostic factors in patients with recurrent intrahepatic cholangiocarcinoma after curative resection: A retrospective cohort study. Int J Surg 54:156-162, 2018
- Honmyo N, Kobayashi T, Hamaoka M, et al: Comparison of new prognostic systems for patients with resectable hepatocellular carcinoma: Albumin-Bilirubin grade and Albumin-Indocyanine Green Evaluation grade. Hepatol Res 49:1218-1226, 2019
- Yamamoto M, Kobayashi T, Oshita A, et al: Laparoscopic versus open limited liver resection for hepatocellular carcinoma with liver cirrhosis: a propensity score matching study with the Hiroshima Surgical study group of Clinical Oncology (HiSCO). Surg Endosc 34:5055-5061, 2020
- Honmyo N, Kobayashi T, Kuroda S, Oshita A, Onoe T, Kohashi T, Fukuda S, Ohmori I, Abe T, Imaoka Y, Akita T, Tanaka J, Ohdan H.: A novel model for predicting posthepatectomy liver failure based on liver function and degree of liver resection in patients with hepatocellular carcinoma. HPB (Oxford). 2021 Jan;23(1):134-143. doi: 10.1016/j.hpb.2020.05.008. Epub 2020 Jun 18. PMID: 32563594
- Yamamoto M, Kobayashi T, Honmyo N, Oshita A, Abe T, Kohashi T, Onoe T, Fukuda S, Omori I, Imaoka Y, Ohdan H.: Liver resection is associated with good outcomes for hepatocellular carcinoma patients beyond the Barcelona Clinic Liver Cancer criteria:A multicenter study with the Hiroshima Surgical study group ofClinical Oncology. Surgery. 2021 Oct 29;S0039-6060(21)00891-6. doi: 10.1016/j.surg.2021.09.009.
- Imaoka Y, Ohira M, Kobayashi T, Honmyo N, Hamaoka M, Onoe T, Abe T, Oishi K, Inoue M, Ohdan H Impact of Geriatric Nutritional Risk Index After Initial Hepatectomy for Hepatocellular Carcinoma: a Retrospective Cohort Study with the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)
- Ohira M, Kobayashi T, Hamaoka M, Abe T, Onoe T, Inoue M, Honmyo N, Oishi K, Ohdan H & Hiroshima Surgical study group of Clinical Oncology (HiSCO) Prognosis of repeat hepatectomy for liver transplantable hepatocellular carcinoma recurrence after hepatectomy: a Retrospective Cohort Study with the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)
- Namba Y, Kobayashi T, Hashimoto M, Onoe T, Mashima H, Oishi K, Honmyo N, Abe T, Kuroda S, Ohdan H The efficacy and safety of pure laparoscopic liver resection for hepatocellular carcinoma in super-elderly patients over 80 years: A multicenter propensity analysis
- Hashimoto M, Kobayashi T, Ohira M, Okimoto S, Abe T, Inoue M, Onoe T, Honmyo N, Kuroda S, Ohdan H Comparison of postoperative outcomes in cases achieving sustained virological response with direct-acting antiviral and interferon therapy
- Tadokoro T, Kobayashi T, Honmyo N, Kuroda S, Ohira M, Hashimoto M, Oishi K, Oshita A, Abe T, Onoe T, Kohashi T, Ohdan H Albumin-Butyrylcholinesterase as a Novel Prognostic Biomarker for Hepatocellular Carcinoma Post-hepatectomy: A Retrospective Cohort Study with the Hiroshima Surgical Study Group of Clinical Oncology
- MEDICAL TRIBUNEにHiSCO肝癌共通データベースの記事が掲載されました。
大腸癌共通データベース
- Bekki T, Shimomura M, Adachi T, Miguchi M, Ikeda S, Yoshimitsu M, Kohyama M, Nakahara M, Kobayashi H, Toyota K, Shimizu Y, Sumitani D, Saito Y, Takakura Y, Ishizaki Y, Kodama S, Fujimori M, Hattori M, Shimizu W, Ohdan H. Predictive factors associated with anastomotic leakage after resection of rectal cancer: a multicenter study with the Hiroshima Surgical study group of Clinical Oncology. Langenbecks Arch Surg, 408: 199, 2023.
- Imaoka K, Shimomura M, Hattori M, Adachi T, MD, Shimizu W, MD, Miguchi M, MD, Ikeda S, Yoshimitsu M, MD, Kohyama M, Nakahara M, MD, Kobayashi H, Kochi M, Shimizu Y, Sumitani D, Ohdan H, Weekday Surgery Associated With Short-term Outcomes in Patients With Colorectal Cancers Care NET
- Imaoka K, Shimomura M, Okuda H, Yano T, Shimizu W, Yoshimitsu M, Ikeda S, Nakahara M, Kohyama M, Kobayashi H, Shimizu Y, Kochi M, Akabane S, Sumitani D, Mukai S, Takakura Y, Ishizaki Y, Kodama S, Fujimori M, Ishikawa S, Adachi T, Hattori M, Ohdan H Intraoperative Blood Loss Predicts Local Recurrence After Curative Resection for Stage I–III Colorectal Cancer
- Imaoka K, Shimomura M, Okuda H, Yano T, Shimizu W, Yoshimitsu M, Ikeda S, Nakahara M, Kohyama M, Kobayashi H, Shimizu Y, Kochi M, Sumitani D, Mukai S, Takakura Y, Ishizaki Y, Kodama S, Fujimori M, Ishikawa S, Adachi T, Ohdan H. Multivisceral resection as a key indicator of recurrence in locally advanced colorectal cancers with pathologic T3 tumors. J Gastrointest Surg. 2025 May;29(5):102015. doi: 10.1016/j.gassur.2025.102015. Epub 2025 Mar 11. PMID: 40081790.
胃癌共通データベース
- Fujikuni N, Tanabe K, Hattori M, Yamamoto Y, Tazawa H, Toyota K, Tokumoto N, Hotta R, Yanagawa S, Saeki Y, Sugiyama Y, Ikeda M, Shishida M, Fukuda T, Okano K, Nishihara M, Ohdan H, On Behalf Of Hiroshima Surgical Study Group Of Clinical Oncology Hi SCO. Distal Gastrectomy for Symptomatic Stage IV Gastric Cancer Contributes to Prognosis with Acceptable Safety Compared to Gastrojejunostomy. Cancers (Basel), 14, 2022.
- Yanagawa S, Tanabe K, Kano M, Hotta R, Saeki Y, Fujikuni N, Ohdan H, on behalf of Hiroshima Surgical Study Group of Clinical Oncology (HiSCO) Clinicopathological features of hepatoid adenocarcinoma of the stomach: A multicenter retrospective study
- Toyota K, Tanabe K, Kano M, Komo T, Hotta R, Yanagawa S, Saeki Y, Tazawa H, Ikeda M, Shishida M, Okano K, Ide R, Imaoka Y, Takahashi S, Ohdan H, Hiroshima Surgical Study Group of Clinical O. Predictors of Tolerability for Postoperative Adjuvant S1 Plus Docetaxel Chemotherapy for Gastric Cancer: A Multicenter Retrospective Study. Gastric Cancer;28(1):102-111, 2025.
- Mikihiro Kano, Noriaki Tokumoto, Kazuaki Tanabe, Jun Hihara, Kazuhiro Toyota, Ryuichi Hotta, Yoshihiro Saeki, Hirofumi Tazawa, Nobuaki Fujikuni on behalf of Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)
心臓血管外科共通データベース
- Okazaki T, Kobayashi T, Mochizuki S, Ozawa M, Maeda K, Inoue R, Futagami D, Tachibana H, Sato K, Hiraoka T, Tomota M, Emura S, Shimizu H, Takasaki T, Kodama H, and Shinya Takahashi. Clinical Outcomes of Common Femoral Thromboendarterectomy with Bovine Pericardium Patch Angioplasty. Annals of Vascular Surgery 2024; 98: 194-200.
- Shimizu H, Kobayashi T, Okazaki T, Mochizuki S, Maeda K, Sato T, Emura S, Arai Y, Kato Y, Takahashi S. Clinical impact of fluoropolymer-based drug-eluting stent thrombosis in femoropopliteal artery occlusive lesions. Vascular 2024. doi: 10.1177/17085381241258553.
- Maeda K, Kobayashi T, Emura S, Okazaki T, Mochizuki S, Sato T, Taniguchi M, Futagami D, Inoue R, Tomota M, Hiraoka T, Shimonaga T, Tachibana H, Shimizu H, Takahashi S. Medium-Term Outcomes of Treatment with a VIABAHN VBX Covered Stent for Aortoiliac Occlusive Lesions in Patients with Peripheral Artery Disease. Annals of Vasc Surg 2024; 105: 201-208.
HiSCO-MCFG試験 試験終了
深在性真菌症(外科・集中治療領域)の経験的治療におけるミカファンギンの有用性に関する多施設共同研究
